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Vivafarma Solutions Ltd.
Vivafarma Solutions Ltd. - Sofia


16.00 BGN
13.00 BGN
Dosage form:
30 ml
Suppresses the penetration of the virus into the cells of the upper respiratory tract
4 sprays directly in the throat




Please read the package leaflet carefully before use!

ZIVEX INNOVATIVE ORAL SPRAY is a medical device. Forms a protective biofilm on the mucous membrane of the throat with broad antiviral and antimicrobial activity. ZIVEX is used to treat sore throats associated with soreness, difficulty swallowing, burning, including when these are symptoms of pharyngitis or tonsillitis. It can be used as a preventative measure if you are often exposed to environmental irritants such as cold, smoke, smog and dust. Scientific tests show inhibition of 99.9% of viruses, including the SARS-CoV-2 coronavirus, in just 30 seconds.

Zivex Inovate Oral Spray is suitable for nasal and throat sprays, specially designed to form a protective layer of mucus in the mouth and nasal cavity to prevent the growth of viruses and bacteria. Developed with a technology that Crab Sinergy has been using in various products for more than a decade, when sprayed, they form a barrier of acidic and hypertonic environment with an adhesive component that attaches them to the mucus. This barrier action is enhanced by quercetin, which has a specific effect on the mechanisms of penetration of SARS-CoV-2 virus into nasal and oral mucosal cells, with a well-studied antiviral effect and against influenza H1N1 virus.

Zivex Inovate Oral Spray acts on three levels on the mechanisms of viral proliferation:

They form an adhesive barrier with an acidic pH, which blocks the viruss contact with the epithelial cells of the oral and nasal mucosa. Barriers composed of cellulose-based substances associated with acidic pH inhibit the proliferation of various respiratory viruses. Contact between the virus and the cells is prevented by a biofilm formed on the cell epithelium.

The barrier effect is enhanced and becomes specific against SARS-CoV-2 with the help of the antiviral active ingredient, Quercetin. Quercetin in the screening of more than 8,000 substances ranks 5th in strength for its ability to inhibit the binding of the SARS-CoV-2 Spike protein to the ACE2 receptor on the surface of oral and nasal mucosal cells. Quercetin is also an inhibitor of the 3Cl protease, a major enzyme for the penetration of SARS-CoV-2 into host cells and a regulator of miRNA gene expression by interrupting viral genome expression.

Quercetin has a specific antiviral effect by blocking the entry of influenza H1N1 virus into airway cells. Zivex Modern Oral Spray has an Italian patent, which by incorporating Quercetin into liposomes based on soy phospholipids (phosphatidylcholine), makes it more soluble in water until a sufficient concentration is obtained for antiviral effect. Quercetin is water-soluble in microparticles of phosphatidylcholine at a concentration of 1: 1, which are microdispersed in aqueous medium.

In case of upper respiratory tract infection, Quercetin has a triple action:

  • Suppresses the penetration of the virus into the cells of the upper respiratory tract
  • Has anti-inflammatory action, which regulates the release of cytokines and reduces the symptoms of the upper respiratory tract
  • Has an immunomodulatory effect on the immune system

Zivex Inovate oral spray is used for infections of the mucous membranes of the mouth and throat (pharyngitis, tonsillitis) accompanied by painful swallowing, inflammation of the gums and colds. Based on the rapid penetration and local accumulation in the inflamed tissue, a rapid reduction in discomfort and pain when swallowing is achieved.

Precautions: Keep out of reach of children. The spray is for personal use only. Do not use if you are hypersensitive or allergic to any of the ingredients. In case of side effects, stop treatment and seek medical help. Do not use in children under 3 years of age.

Ingredients: Purified Water, Saccarosa, Hydroxy propylmethylcellulose, Cetylpyridine, Citric Acid, Polysorbate 80, Eucalyptol, Coloring Agent Aroma, Quercetin, Xylitol

Directions for use: Shake the vial before use. Spray 4 times directly on the sore spot in your mouth. Repeat every 3 hours if necessary. Do not use in children under 3 years.

Storage: Store in the original package at a temperature below 30 ° C. Keep away from direct sunlight and store in a dry and cool place.