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Vivafarma Solutions Ltd.
Vivafarma Solutions Ltd. - Sofia


15.40 BGN

Taking care of your nose hygiene has never been easier. ..

ZYME is the right choice for children and adults with stuffy and runny nose!

Active ingredient: LYZOZYME + ISOTONIC SALINE (0.9% NaCl)


  1. What is LYSOZYME?
  2. What is ZYME?
  3. Composition:
  4. Aplication:
  5. Dosage:
  6. How to use ZYME nasal spray?
  7. Precautions:
  8. How to store Zyme Nasal Spray?
  9. Clinical data:
  10. What is LYSOZYME?

Lysozyme is enzyme found in the secretions (tears) of the lacrimal glands of animals and in nasal mucus, gastric secretions, and egg white.

Lysozyme, is an antimicrobial enzyme produced by animals that forms part of the innate immune system. Discovered in 1921 by Sir Alexander Fleming, lysozyme catalyzes the breakdown of certain carbohydrates found in the cell walls of certain bacteria (e.g., cocci). It thus functions, in the case of lacrimal fluid, to protect the cornea of the eye from infection.

2.What is ZYME?

ZYME isotonic (0.9% NaCl saline) augmented with LYSOZYME NASAL spray for INFANTS, CHILDREN AND ADULTS 30 ml

ZYME is an innovative nasal spray containing Lysozyme and isotonic saline (0.9% NaCl).

ZYME nasal spray is a medical device. Lysozyme is one of the most powerful natural antibacterial agents, normally found in a number of human secretions such as mucus, saliva and tears. Lysozyme attacks the peptidoglycans found in the cell wall of bacteria and In particular, gram-positive bacteria, has viral, bactericidal and antifungal action in the nasal cavity and paranasal sinuses. The isotonic solution complements the action of Lysozyme by liquefying nasal secretions and has antimicrobial and lavage action, reduces the risk of complications after colds and flu, increases the local immunity of the nasal mucosa.

ZYME flushes, liquefies and removes nasal secretions, maintaining the physiological concentration of lysozyme in the nasal mucosa and preventing the adverse effects of ordinary isotonic and hypertonic solution.


Water, Lysozyme and 9g/l NaCl

  1. Application:

Daily nasal hygiene of infants and children

  • Irritation and dryness of the nasal mucosa
  • Bacterial overgrowth
  • Colonization of the nasal mucosa
  • After surgery and addition to the treatment of ENT infections
  • Acute and chronic bacterial sinusitis
  • Acute or allergic rhinitis in respiratory infections (influenza and parainfluenza
  1. Dosage:

One injection in each nostril 4-6 times a day to unclog the nose and maintain the natural protective power of the nasal mucosa. For children and adults over 0+ years of age.

  1. How to use Zyme nasal spray?

Insert the nozzle into each nostril and spray one or more times. After use, please put the protective cap back on the tip. Repeat this process as needed. Zyme nasal spray contains safe and natural ingredients and may be suitable for long-term use. If necessary, in infants, children and adults, after a recommendation from a doctor or pharmacist.

  1. Precautions:

Do not use in case of a known allergy to any of the ingredients of the product. In case of hypersensitivity, please stop using the product and contact your doctor. Keep out of reach of children under 3 years. Do not use after the expiration date of the outer box.

  1. How to store Zyme Nasal Spray?

Please store the product at a temperature below 30 ° C and away from direct sunlight.

Zyme is a 30 ml nasal spray with a patented nasal applicator, suitable for use by all age groups.

  1. Clinically tested!

We tested Zyme on 20 patients, comparing the antimicrobial activity of nasal secretions after nasal lavage with plain isotonic and hypertonic solution and Zyme nasal spray containing lysozyme.

The effect of saline (NaCl 0.9%) was tested in healthy volunteers. The antimicrobial activity of sinus secretion decreases by approximately 25% during the first 6 hours, which can lead to unwanted bacterial overgrowth and colonization of the nasal mucosa. This is particularly common in patients instructed to flush their nasal cavity repeatedly during the day, potentially leaving the epithelium with reduced levels of antimicrobial peptides for an average period of 24 hours (Woods CM et al. Int. Forum Allergy & Rhinology, vol. 5 (12), 1104-1110)


Crab Synergy - Italy

Marketing Authorization Holder: Viva Pharma Solutions

Packaging: 30 ml

ZYME is a medical device CE:

Read the package leaflet before use!